:root {
  --primary: #0f766e;
  --primary-dark: #115e59;
  --bg: #f4f7f6;
  --card: #ffffff;
  --text: #1f2937;
  --text-light: #6b7280;
  --border: #e5e7eb;
  --danger: #b91c1c;
  --radius: 12px;
  --shadow: 0 1px 3px rgba(0, 0, 0, 0.08);
}

* { box-sizing: border-box; }

.visually-hidden {
  position: absolute;
  width: 1px;
  height: 1px;
  padding: 0;
  margin: -1px;
  overflow: hidden;
  clip: rect(0, 0, 0, 0);
  white-space: nowrap;
  border: 0;
}

body {
  margin: 0;
  font-family: -apple-system, BlinkMacSystemFont, "PingFang SC", "Microsoft YaHei", "Helvetica Neue", Arial, sans-serif;
  background: var(--bg);
  color: var(--text);
  line-height: 1.6;
}

.container {
  max-width: 960px;
  margin: 0 auto;
  padding: 0 20px;
}

.site-header {
  background: linear-gradient(135deg, var(--primary), var(--primary-dark));
  color: #fff;
  padding: 20px 0;
}

.header-inner {
  display: flex;
  align-items: baseline;
  justify-content: space-between;
  flex-wrap: wrap;
  gap: 8px;
}

.brand {
  color: #fff;
  text-decoration: none;
  display: flex;
  align-items: center;
  gap: 10px;
}

.brand-mark {
  width: 38px;
  height: 38px;
  border-radius: 10px;
  background: rgba(255, 255, 255, 0.18);
  display: inline-flex;
  align-items: center;
  justify-content: center;
  font-size: 20px;
  font-weight: 700;
}

.brand-name {
  font-size: 20px;
  font-weight: 700;
}

.brand-name small {
  font-size: 12px;
  font-weight: 400;
  opacity: 0.85;
}

.tagline {
  margin: 0;
  font-size: 13px;
  opacity: 0.92;
}

main { padding: 24px 0 40px; }

.search-box input {
  width: 100%;
  padding: 14px 18px;
  font-size: 16px;
  border: 2px solid var(--border);
  border-radius: var(--radius);
  outline: none;
  background: var(--card);
  box-shadow: var(--shadow);
}

.search-box input:focus {
  border-color: var(--primary);
}

:focus-visible {
  outline: 3px solid #0e7490;
  outline-offset: 3px;
}

.category-bar {
  display: flex;
  flex-wrap: wrap;
  gap: 8px;
  margin: 16px 0 20px;
}

.chip {
  border: 1px solid var(--border);
  background: var(--card);
  color: var(--text-light);
  border-radius: 999px;
  padding: 6px 14px;
  font-size: 13px;
  cursor: pointer;
  transition: all 0.15s ease;
}

.chip:hover {
  border-color: var(--primary);
  color: var(--primary);
}

.chip.active {
  background: var(--primary);
  border-color: var(--primary);
  color: #fff;
}

.disease-grid {
  display: grid;
  grid-template-columns: repeat(auto-fill, minmax(280px, 1fr));
  gap: 16px;
}

.disease-card {
  display: block;
  background: var(--card);
  border: 1px solid var(--border);
  border-radius: var(--radius);
  padding: 18px;
  box-shadow: var(--shadow);
  cursor: pointer;
  color: inherit;
  text-decoration: none;
  transition: transform 0.15s ease, box-shadow 0.15s ease;
}

.disease-card:hover {
  transform: translateY(-2px);
  box-shadow: 0 6px 16px rgba(0, 0, 0, 0.1);
}

.card-top {
  display: flex;
  align-items: center;
  justify-content: space-between;
  gap: 10px;
}

.card-top h2 {
  margin: 0;
  font-size: 18px;
}

.badge {
  background: #e6f4f1;
  color: var(--primary-dark);
  border-radius: 6px;
  padding: 2px 8px;
  font-size: 12px;
  white-space: nowrap;
}

.card-overview {
  margin: 10px 0 0;
  color: var(--text-light);
  font-size: 14px;
  display: -webkit-box;
  -webkit-line-clamp: 2;
  -webkit-box-orient: vertical;
  overflow: hidden;
}

.empty-state {
  text-align: center;
  color: var(--text-light);
  padding: 48px 0;
}

.hidden { display: none; }

.back-button {
  border: 1px solid var(--border);
  background: var(--card);
  color: var(--primary-dark);
  border-radius: 8px;
  padding: 8px 14px;
  font-size: 14px;
  cursor: pointer;
  margin-bottom: 16px;
}

.back-button:hover {
  border-color: var(--primary);
}

.detail-header {
  background: var(--card);
  border: 1px solid var(--border);
  border-radius: var(--radius);
  padding: 24px;
  box-shadow: var(--shadow);
}

.detail-header h1 {
  margin: 0 0 6px;
  font-size: 26px;
}

.detail-section {
  background: var(--card);
  border: 1px solid var(--border);
  border-radius: var(--radius);
  padding: 20px 24px;
  margin-top: 16px;
  box-shadow: var(--shadow);
}

.detail-section h2 {
  margin: 0 0 10px;
  font-size: 18px;
  color: var(--primary-dark);
}

.detail-section ul {
  margin: 0;
  padding-left: 20px;
}

.detail-section li {
  margin-bottom: 6px;
}

.source-list a,
.report-link {
  color: var(--primary-dark);
  text-underline-offset: 3px;
}

.source-meta {
  color: var(--text-light);
  font-size: 13px;
  margin: 10px 0;
}

.report-link {
  display: inline-block;
  font-size: 14px;
  font-weight: 600;
}

.disclaimer-box {
  background: #fdf3f3;
  border: 1px solid #f3c1c1;
  color: var(--danger);
  border-radius: var(--radius);
  padding: 14px 18px;
  margin-top: 16px;
  font-size: 14px;
}

.site-footer {
  background: #e9efed;
  color: var(--text-light);
  padding: 24px 0;
  font-size: 13px;
}

.site-footer p { margin: 4px 0; }

.credit {
  margin-top: 10px !important;
  font-size: 12px;
}

@media (max-width: 600px) {
  .header-inner { flex-direction: column; }
  .detail-header h1 { font-size: 22px; }
}